Treatments for fungal infections

Antifungal drugs are used to treat mycoses. Depending on the nature of the infection, a topical or systemic agent may be used.

Polyene antifungals

• Amphotericin B
• Natamycin
• Rimocidin
• Filipin
• Nystatin
• Amphotericin B
• Candicin
• Hamycin

Azole antifungal

Imidazole, triazole, and thiazole antifungals
Imidazoles

• Miconazole
• Ketoconazole
• Clotrimazole
• Econazole
• Omoconazole
• Bifonazole
• Butoconazole
• Fenticonazole
• Isoconazole
• Oxiconazole
• Sertaconazole
• Sulconazole
• Tioconazole

Triazoles

• Fluconazole
• Itraconazole
• Isavuconazole
• Ravuconazole
• Posaconazole
• Voriconazole
• Terconazole

Thiazoles

• Abafungin

Allylamines antifungal

• Terbinafine
• Naftifine
• Butenafine

Echinocandins antifungal

• Anidulafungin
• Caspofungin
• Micafungin

Others antifungal

• Polygodial – most useful against Candida albicans
• Benzoic acid – has antifugal properties but must be combined with a keratolytic agent
• Ciclopirox – (ciclopirox olamine) – most useful against Tinea versicolour
• Tolnaftate
• Undecylenic acid – acid derived from natural castor oil; fungistatic as well as anti-bacterial and anti-viral
• Flucytosine or 5-fluorocytosine – an antimetabolite
• Griseofulvin
• Haloprogin – discontinued
• Sodium bicarbonate (NaHCO3)

Antifungal alternatives

• Allicin – (from crushing garlic)
• Tea tree oil
• Citronella oil – obtained from different species of Cymbopogon (Lemon grass)
• Iodine
• olive leaf
• orange oil
• palmarosa oil
• patchouli
• lemon myrtle
• Neem Seed Oil
• Coconut Oil
• Zinc – in dietary supplements or natural food sources
• Selenium – in dietary supplements or natural food sources
• Horopito (Pseudowintera colorata) leaf

Lasers treatments

Lasers are being used for treatment of toenail fungus. This treatment is safe and has no side effects since the laser is applied directly to the infection.